Extracellular Vesicles as Mediators of Cellular Cross Talk in the Lung Microenvironment
نویسندگان
چکیده
منابع مشابه
Extracellular Vesicles As Mediators of Cardiovascular Calcification
Involvement of cell-derived extracellular particles, coined as matrix vesicles (MVs), in biological bone formation was introduced by Bonucci and Anderson in mid-1960s. In 1983, Anderson et al. observed similar structures in atherosclerotic lesion calcification using electron microscopy. Recent studies employing new technologies and high- resolution microscopy have shown that although they exhib...
متن کاملExtracellular vesicles in the hematopoietic microenvironment
Self-renewal and differentiation are defining characteristics of hematopoietic stem and progenitor cells, and their balanced regulation is central to lifelong function of both blood and immune systems. In addition to cell-intrinsic programs, hematopoietic stem and progenitor cell fate decisions are subject to extrinsic cues from within the bone marrow microenvironment and systemically. Yet, man...
متن کاملPulmonary Extracellular Vesicles as Mediators of Local and Systemic Inflammation
Cells of the airways are constantly exposed to environmental hazards including cigarette smoke, irritants, pathogens, and mechanical insults. Maintaining barrier integrity is vital, and mounting responses to threats depends on intercellular communication. Extracellular vesicles (EVs), including exosomes and microvesicles, are major signal mediators between cells, shuttling cargo in health and d...
متن کاملExtracellular vesicles as mediators of neuron-glia communication
In the nervous system, glia cells maintain homeostasis, synthesize myelin, provide metabolic support, and participate in immune defense. The communication between glia and neurons is essential to synchronize these diverse functions with brain activity. Evidence is accumulating that secreted extracellular vesicles (EVs), such as exosomes and shedding microvesicles, are key players in intercellul...
متن کاملParasite Extracellular Vesicles: Mediators of Intercellular Communication
The 2013 Nobel Prize in Physiology or Medicine recognized pioneering research on secretion of proteins outside the cell and the delivery of selected cargo to specific intracellular compartments via secretory vesicles. This seminal work, performed in yeast and mammalian cells, defined multiple vital roles vesicles play in cellular physiology. Recent studies have revealed the critical role of ves...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Medicine
سال: 2020
ISSN: 2296-858X
DOI: 10.3389/fmed.2020.00326